Life can be hectic for a newly single father and successful stand-up comedian – just ask Louie, a fictionalised version of comic Louis C.K., who portrays the character. From his first meeting of the PTA to dating again and navigating the big city with two small children, the comic shares pieces of his day with an appreciative audience during his stand-up gigs. The series features a number of stand-up comedians appearing in the show as fictionalised versions of themselves. In addition to starring in the show, Louis C.K. also created it.