A night-shift doctor at San Antonio Memorial, T.C. Callahan struggles to find the balance between saving lives and the hard reality of running a hospital. Every day is a battle with the new manager, Michael Ragosa, whose main focus is implementing cost-cutting measures and whom T.C. defies every chance he gets. Ragosa’s second-in-charge — and T.C.’s ex-girlfriend — Jordan, attempts to use their shared past to keep him in line, but that seems futile, as T.C. isn’t afraid to stand up to anyone and is prepared to see this fight to its finish.